Patrick Dangerfield is critical of Sam Newman after host of The Footy Show made insensitive remarks against the LGBTIQ community.

"I just think Sam was well off the mark and well out of line," Dangerfield said about Newman's comments.

"It's been a history. It's been something that has been happening for such a long period of time and they will continue to run with it because it will continue to rate."

Newman had been asked by fellow presenter and Geelong hero Billy Brownless if he knew who Jenner was, replying: "I know who he ... it is oh well what is she? Is it a he or a she? Is it transgender, is it?"

Newman has since issued a brief statement, saying: "I regret the comments I made about Caitlyn Jenner. What I said was not appropriate and I'm sorry to anyone offended."

Dangerfield said he had appeared on the Footy Show once and he felt for players who appeared on the panel during controversial moments like Wednesday night's.

"You certainly don't want to be part of an episode that has commentary around that because it puts you in a really uncomfortable position as a player sitting on the panel," he said.

"But it's really difficult to stand up and say I don't agree with this right at the moment it is said. The program infrastructure doesn't allow it to happen."