Geelong's narrow loss to St Kilda takes a heavy toll with four of the Cats' premiership players to miss this week.
Matthew Scarlett, Cameron Ling, Darren Milburn and James Kelly have all been sidelined.
The loss of All-Australian defenders Scarlett and Milburn has opened the door for 19-year-old Tom Gillies to make his debut, while Ryan Gamble, David Wojcinksi and Tom Lonergan come back into the side.
Scarlett has back tightness, Ling has knee tendonitis, Milburn rolled his ankle and Kelly was left out after pulling up this week with a tight hamstring. Kelly and Scarlett are expected to return for the round 16 game against Melbourne, while the club last night said Ling's condition would be monitored over the next week.